Activity
Mon
Wed
Fri
Sun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
What is this?
Less
More

Memberships

The Gear Bible

237 members • Free

OPTIMIZE & THRIVE

5.3k members • Free

Optimized Living

3.5k members • Free

Pharmacology Teaching System

174 members • Free

DivineBougie

1.8k members • Free

The Peptide Collective

294 members • $75

PBN Collective

514 members • Free

Tony Huge Evolution

3.9k members • Free

8 contributions to Pharmacology Teaching System
Brain health / cognition / memory
Not sure about yall, but Alzheimer's is in the wood pile for me. With that in mind I am very curious about brain health and performance. I am curious what you do to help your brain/cognition/memory. I am currently taking creatine (10g ED) for the brain and muscle benefits. I have tried P21 and Dihexa. The jury is still out on Dihexa. I think I will give it another swing once I get through the month of May(its a busy month). P21 seemed to help, but now it seems scarce so doing follow research is not happening. I suspect some of you have way more knowledge, about brain performance, than me since my idea of prepping my mind for study was to pound coffee.
2
0
First cycle
In your opinion what would recommend for somebody that is young but plans to run more cycles blast and cruise or pct?
2 likes • Apr 20
Do you want to have kids later? If so PCT. If I remember rightly you are still on the young end. PCT is probably the answer until you are sure you don't want kids and that is "you have a vasectomy" sure. We have talked before and you know what I think. I would be glad to bounce ideas off each other because shutting down your nuts is a big deal in the long run. When I say ideas not just the PCT part but what its like on the TRT side and having kids. I've done both. Really some people know they don't want kids, others just think they don't want them and its they just don't want them now.
2 likes • Apr 21
@Julian Wright yeah I hear you. You might have to look into HCG to keep the nuts good. There is some good YT and info out there. Look for stuff from Dr Crisler.
How an Experiment Tried to Turn Off the Muscle’s “Brake”
The human body is not designed for unlimited growth. There is a molecular system whose purpose is exactly that: to impose a limit. At the center of this system is a protein known as 🔵myostatin (GDF-8)🔵. Its role is straightforward:to inhibit skeletal muscle hypertrophy. How it works under normal conditions Myostatin binds to a receptor on the surface of muscle cells called ActRIIB. This interaction activates an intracellular signaling pathway: 🔴SMAD2/3🔴 The outcome is a clear biological signal:reduce muscle cell growth and differentiation. This is a regulatory mechanism, not a defect. What ACE-031 does ACE-031 is a recombinant fusion protein engineered to interfere with this process. Instead of blocking the receptor at the cellular level, it operates differently: it circulates in the bloodstream and functions as a soluble decoy receptor. This means it binds myostatin before it can reach its natural receptor. What happens at the molecular level When myostatin is sequestered: ⚠️it cannot bind to ActRIIB ⚠️SMAD2/3 signaling is not activated ⚠️the inhibitory signal is effectively removed The result is a physiological environment more permissive to muscle growth. The critical detail ACE-031 is not selective for myostatin. It also binds other ligands within the same signaling network, including: - activins - members of the BMP family, such as BMP-9 These molecules are not limited to muscle regulation. They also play key roles in vascular homeostasis and endothelial signaling.
How an Experiment Tried to Turn Off the Muscle’s “Brake”
1 like • Apr 11
I may understand what you are getting at in the "The Critical Details" part but you might want to break it down Barney style for people.
Hemogenin / oxymetolone
Planning to use this for bonemass gains, anyone has a clue about its intake? Saw somewhere that it would regularly be 50mg a day but a guy ik who used lots of roids told me to do 25mg a week if I just wanted the bone raises, although I’m asking cause it seems off and weird to go from 50mg a day normally to 25mg a week, feels like a pretty low dose..
0 likes • Apr 6
Anadrol? You should do some of your own research. Start here: https://www.skool.com/antiet-1213/classroom/ca327b9a Have you taken steroids before? I have you ever taken more than a TRT dose of testosterone? If the answer is is “no” Anadrol is not for you. It’s not a beginner steroid. You can say you bone max all you want but the sides from Anadrol are not worth it. If you want a sturdier frame hit the weights. Get to where you can squat a house and deadlift an elephant. Once you hit your max genetic potential then hit the gear. There is a bone max classroom and no where in it does it say take Anadrol.
0 likes • Apr 6
@Mikey Ms William Llewellyn has a interesting book about ALL the steroids. The dosing he had found was 25-150mg a day for performance (bodybuilding) for 6-8 weeks. You might want to initially start below that level and see how it goes and how sides are for you. just out of curiosity how are you going to determine if you have grown your bones? Dexa? Make sure you pay attention to your Liver values and blood pressure. keep in mind you can stop taking it and let everything return to normal (liver and BP) and try again. Let us know how it goes. I think it would be some good info for others. Im 57 so there is no real bone growth in my future. Just keeping what I have.
Product sourcing
Anyone know where to source anastrozole,letrozole,exemestane in Europe ? Is indiamart an option ?
1 like • Apr 2
Search for Rohit, Dilip, or Vishu. Those are the three that I have had luck with.
1 like • Apr 3
@Barbara F they ship to the US. That’s where I’m at.
1-8 of 8
Joe Hart
2
5points to level up
@joe-hart-6175
Better living through chemistry

Active 3h ago
Joined Jan 25, 2026