Personal Experience Update: I know we already did a deep dive on Tesamorelin, so I wanted to share my personal experience with it so far, because this was a good reminder that protocols don’t always play out the same way for everyone. I started at 250mcg and tolerated it really well the first week. Since everything seemed good, I increased it to 500mcg. Within that week I noticed pretty significant water retention and the scale went up almost 8 pounds. Now logically I knew there was no possible way to gain that much fat that fast — but seeing the number jump like that definitely messes with your head a little. I decided to stick it out another week to see if my body would adjust… but the water retention didn’t change. So I dropped back down to 250mcg, which is where I’m currently at, and the water weight has already started coming back down again. It was honestly surprising how just a small dose increase made such a big difference. Some people’s bodies are just more sensitive to certain peptides, and I think I’m probably one of those people. My protocol originally had me titrating up to 1mg by June 16, but this experience reminded me that more isn’t always better. Sometimes the smartest move is listening to your body and adjusting, even if that means staying at a lower dose or moving up more slowly. Curious if anyone else here has had a similar experience with Tesamorelin — especially when increasing doses. Did your body eventually adjust or did lowering the dose help?

A lot of you have been asking… how do I even start? 🤍 Here’s the simplest way to approach it: Option 1 (guided + medical): If you want structure, labs, and supervision—this is the route I’d recommend. A telehealth doctor, personalized plan, and check-ins: https://elliemd.com/coribosco or defymedical.com Option 2 (on your own): If you feel confident doing your own research, this is what I personally use. Full 3rd party testing reports They come in powder form and you’ll reconstitute. https://atomiklabz.com/aff/197/ https://solutionpeptides.net/aff/197/ Use CORI15 or CORI25 These are labeled for research purposes. (Reta, Sema, NAD+, Peptides, Vitamins) Helpful tip: – Tirzepatide = Peptide-2 (T) – Retatrutide = Peptide-3 (R) My recommendations if you’re new: – Start LOW (micro-dose and assess) – Don’t stack multiple things right away – Use a peptide calculator before mixing – Keep it simple and intentional There’s a learning curve—but once you understand it, it’s actually very manageable. Start simple. Build smart. 🤍

Where are you at with BPC-157?

I feel like a lot of people get this backwards when it comes to peptides and “biohacking.” So many people jump straight into stacking things without first making sure the foundation is dialed in. For me, one of the biggest things was getting bloodwork done and optimizing my hormones. I actually started testosterone pellets back in 2023 through a local provider and saw a huge benefit just from that alone — my energy improved a lot. The only downside with pellets is they can feel a little inconsistent and they’re hard to adjust once they’re inserted. But it allowed me to also get my lab work done every 12 weeks and check my hormone levels. Just this week I met with Defy Medical after seeing a lot of people in another group I’m part of mention them for going through labs and hormone optimization and testosterone injections which I think may be more consistent and allow adjustments if needed. They review everything with you — hormones, testosterone levels, and anything else that might need attention. My initial consult was $325, they ordered labs, and I just took the lab order to Quest and ran it through my insurance. What was really interesting is that these labs were done about 3–4 months after my last labs and since then I had started peptides, and a lot of my markers had actually improved. I’ll be honest, I was a little nervous to see the results because even though I feel great, you always wonder if your bloodwork is going to reflect that too. Thankfully it did, which was really reassuring. It was a good reminder that sometimes it’s not about adding a bunch of random things — it’s about understanding your body and filling in the gaps where needed. Once that foundation is there, then things like peptides can become another tool to support your goals. Just sharing what I’m personally doing and what I’m learning along the way. Educational purposes only — not medical advice.

A lot of you message me saying you’re curious about peptides but also a little nervous to start… and honestly that’s completely fair. One option that can make it feel a lot more comfortable is going through a medical platform where a provider actually reviews your health information before anything is ordered. You create an account, fill out your info, and then you can explore options based on your goals — things like weight loss, longevity, skin health, recovery, sexual health, and more. They also have different forms like nasal sprays, oral options, and injections depending on what you’re comfortable with. Just sharing because I know how many questions I get about where to even start. https://elliemd.com/coribosco If you’ve been researching peptides but haven’t taken the leap yet, I’d love to hear what’s holding you back.