๐ฏ If You Could Only Pick THREE - Budget Black Friday Edition
With all these Black Friday deals dropping (check the codes channel! ๐), I keep getting asked: "Derek, if I'm on a budget, what are the essential research peptides that cover all the basics?" This is educational content about research peptides. Always work with healthcare professionals for medical decisions Here's my answer - the three that give you the most complete metabolic optimization: 1๏ธโฃ Retatrutide - The Metabolic Foundation The Mechanism: Triple receptor agonist hitting GIP, GLP-1, AND glucagon. Here's why that matters: - GLP-1: Appetite suppression + improved insulin sensitivity + beta-cell protection - GIP: Direct CNS effects on energy expenditure + preferential subcutaneous fat storage (reducing visceral fat) - Glucagon: Active fat mobilization and oxidation - you're not just eating less, you're BURNING stored fat The Reality: You're addressing insulin resistance, appetite, energy expenditure, and fat metabolism all at once. This is your foundation - if you can only afford ONE compound, this is it. 2๏ธโฃ Tesamorelin OR CJC-1295 (no DAC)/Ipamorelin Why Growth Hormone Pathways Matter: Declining GH is a major driver of increased visceral fat, decreased lean mass, and metabolic dysfunction as we age. Tesamorelin: GHRH analog that specifically targets visceral adipose tissue through enhanced lipolysis. Works through your natural pituitary axis (pulsatile release = better insulin sensitivity than continuous GH). Hits that stubborn belly fat hard while preserving lean mass. 2mg daily dosing. CJC/IPA Combo: Creates optimized GH pulses that mimic natural physiology. CJC amplifies the pulse (2-10x normal GH release), Ipamorelin triggers it without spiking cortisol or prolactin. Better for recovery, sleep architecture, body recomposition, and joint/connective tissue health. Pick based on your goal: Tesamorelin if visceral fat is your primary concern. CJC/IPA if you want overall recovery, sleep quality, and body recomposition. 3๏ธโฃ MOTS-C - The Cellular Optimizer