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Research Peptide Community

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1 contribution to Research Peptide Community
ADHEDONIA/LOSS OF PLEASURE
Let's talk anhedonia from taking glp1s long term. I'm noticing I'm just blah all the time. I'm isolating and just not getting joy from anything anymore. Its also sucked the life out if my libido. Not depressed just blah! I've been doing alot of reading and noticing its an actual side effect for lots of people from long term glp1 use and curious if there's anything that can be done? I mean it makes sense since some people take them for addiction issues and they turn off "food noise" and joy of food. I don't want to stop tho. I honestly want to be on them for life because they do so much more than weight loss for me. I also don't want to not enjoy life. I have so many health issues that are seriously improved. I feel like if i stay on them for life I'll add more time to my clock however, if I'm not enjoying that life is that really worth it? I'm curious if I start taking some dopamine boosting supplements will things get better? Or is there something completely blocking the dopamine channels? I do notice everytime I go up in dose it gets worse. BTW I'm on retatrutide and have been for almost a year but this didn't start until a few months ago.
0 likes • 14d
I don't really want to stop because they do way more than weight loss/ appetite suppression. My entire body is better. I'm just curious if I take supplements if that'll help or if the pathways are just blocked
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Amber Nicholson
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@amber-nicholson-6855
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Active 14d ago
Joined Jul 19, 2025
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