Lesson 1 – The HPT Axis: How Your Brain Controls Testosterone
In this lesson, I break down the HPT Axis: the communication loop between your brain, pituitary, and testes that controls your testosterone and fertility. You’ll learn: • How the hypothalamus releases GnRH to trigger your pituitary • How LH activates Leydig cells to produce testosterone • How FSH stimulates Sertoli cells for sperm production • Why rising estrogen feeds back through Kisspeptin neurons to shut down GnRH • And how therapies like enclomiphene, hCG, and testosterone affect this system Understanding this axis is the foundation of performance medicine. 👉 Comment below what you found most interesting — and what part of this axis you want me to teach next.