Melissa Mantilla – First NED (No Evidence of Disease) after Breast Cancer with Bone Metastasis

Melissa was diagnosed in January 2024 with breast cancer and bone metastasis affecting the vertebrae, sacrum, iliac crest, and ribs. She began standard treatment with Kisqali (ribociclib) and Letrozole, followed by 10 sessions of radiotherapy, which greatly reduced pain and improved mobility.

In May 2024, she added metabolic therapy to her approach, adjusting diet, integrating repurposed drugs, targeted supplements, and lifestyle changes. In June 2025, a PET scan revealed no hypermetabolism — indicating no visible tumors (NED). Melissa continues her protocols to maintain results.

✅ Supplements & Compounds

Core agents used in her integrative approach:

Fenbendazole (Joe Tippens protocol)
CBD oil
Metformin – 1700 mg/day (split into 2 doses)
Dapagliflozin – 10 mg/day
Intravenous Vitamin C – up to 0.25 g/kg per session (titrated to tolerance)
Green tea infusion – daily
Turmeric – homegrown, daily useDietary approach:
Ketogenic diet targeting GKI of 2 (modified over time to ~3–3.5 for energy balance)
Low carb (10–30g/day) from vegetables: broccoli, mushrooms, spinach, onion, garlic
Protein: 1–1.5 g/kg body weight
Fat: ~4x protein intake
Whole foods; avoids processed or “barcode” foods

✅ Therapies & Strategies

Hyperbaric Oxygen Therapy (HBOT) – 20 sessions
Radiotherapy – 10 sessions (initial pain relief and mobility restoration)
Keto metabolic strategy – sustained long-term dietary adherence
Sunlight exposure – daily in tropical climate
Gradual protocol adjustment – modified macros to prevent excess weight loss
Considered but did not use: DON, CDA, 2DG (due to existing progress)

✅ Lab Testing & Monitoring

PET scan – confirmed NED in June 2025
No detailed tumor marker data shared, but progression tracked via imaging
Self-monitoring of GKI for metabolic tracking

✅ Resources & References Shared

Joe Tippens Protocol (fenbendazole + CBD)
Dr. Beckman’s “barcode food” concept
GKI tracking resources for ketogenic therapy
Community encouragement and peer support throughout journey

✅ Key Takeaways

A strict keto diet, fenbendazole, and vitamin C were Melissa’s most impactful interventions (her own view).
Adjusting diet for sustainability (avoiding excessive weight loss) helped maintain energy while staying metabolically targeted.
Integrating repurposed drugs, metabolic strategies, and supportive lifestyle factors contributed to positive outcomes.
Mental and spiritual well-being — kindness toward self, reduced stress, faith, and strong social support — played a central role in healing.
Achieving NED does not end the protocol; Melissa continues her regimen for ongoing prevention and control.

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