Metabolic Therapy Outcomes & Community Insights

Jul 23 (edited) • 🧠 Mindset & Challenges

Gwen Johnson asked a direct and important question: How many of you have seen success with metabolic therapy, and how long did it take? Her curiosity opened the floodgates to one of the deepest community conversations on what success looks like, how it’s measured, and what factors may accelerate or hinder progress.

From impressive remissions to honest struggles with mixed results, members shared timelines, testing data, and real-life insights into what it means to walk the metabolic path. The thread highlighted the need for personalization, patience, mindset, and often—supportive tools like HBOT, repurposed drugs, and deeper diagnostics. It also showed that metabolic therapy is more than a protocol—it’s a philosophy of healing rooted in ownership, curiosity, and community wisdom.

✅ Key Protocol Components Shared

Kimberly Smith: Achieved No Evidence of Disease (NED) by Nov 2024 after combining chemo, Zoledronic Acid, and metabolic therapy starting in Sept 2023. Used GKI targeting, calorie restriction, fasting, HBOT, and off-labels like Metformin, Doxycycline, Mebendazole, Propranolol, Sodium Phenylbutyrate.
Gwen Johnson: Reported her daughter saw a 110-point CA marker drop in 1 month while on metabolic therapy + HBOT. The next month, without HBOT, markers rose by 120 points — raising questions about the critical role of HBOT.
Stuart Briscoe: Explained the glucose + glutamine dual-fuel theory, emphasizing ketogenic diets, glutamine competition via exercise, and therapies that further stress weakened cancer cells. Cited Dr. Makis’ protocol (Ivermectin, Fenbendazole, HBOT, IV Vitamin C).
Simon Lown: Described MT as part science, part mindset. Cautioned that combining MT with aggressive SOC may blunt results due to immune suppression. Advocates for SOC only in life-threatening moments, and favors natural methods, nutrient support, and root-cause investigation over blanket chemo/radiation use.
Odette Rocha: Introduced RGCG testing to identify CTCs (Circulating Tumor Cells) and match supplements/treatments. Too expensive for many, but offers precision.
Nicola Chapman: Shared her experience using Exacta360 test via Astron Health / DataRPGx, accessed through private care after NHS dismissed deeper testing.

✅ Scientific & Philosophical Insights

HBOT appears to play a measurable role in outcomes, potentially amplifying metabolic therapy effectiveness when combined with fasting and glucose restriction.
Standard of care (SOC) can interfere with MT’s mechanisms by suppressing the immune system and creating metabolic chaos; surgical interventions are sometimes viewed as the least damaging of the three (surgery, chemo, radiation).
Success must be defined carefully — is it marker reduction? NED? Symptom relief? Extended survival? Community members offered varied yet valid answers.
Mindset, belief, and autonomy were highlighted as essential — “I will take responsibility for my own care,” as Simon stated.
There is increasing recognition that modern cancer classifications by organ site are outdated, and genetic/microbiome-based tumor profiling is the future.

✅ Practical Wisdom from Community

Track CA markers + GKI over time to identify what’s working.
Don’t remove key therapies (e.g., HBOT) without carefully observing the impact.
Consider testing options like RGCG or Exacta360 when financially possible to personalize therapy.
Low-dose chemo might have a place in future metabolic combinations, but must be weighed carefully.
Community members often build protocols from multiple angles — press-pulse, mitochondrial support, immune modulation, and anti-parasitic layers.
“Success stories” shared on YouTube or Substack should be approached with hope but healthy skepticism — not all provide detailed evidence, but many align with metabolic logic.

✅ Resources & References Shared

Dr. Makis podcast on MT tools: https://makismd.substack.com/p/new-podcast-15-minutes-with-drmakis-306
RGCG testing (mentioned by Odette Rocha) — blood test for CTCs and supplement matching
Astron Health + Exacta360 test (via Nicola Chapman): https://astron.health / https://datarpgx.com
HealingStrong cancer support network (via Odette): https://healingstrong.org
Mentions of Seyfried, D’Agostino, Dr. Peavler, and Dr. Neil Speight as key figures in the MT field

✅ Key Takeaways

Many in the group have seen positive results with metabolic therapy — some achieving full remission or NED in under a year.
HBOT may be a key amplifier of MT outcomes — Gwen’s daughter’s marker rebound without HBOT supports this.
MT success depends on precision, mindset, and removing conflicting therapies when possible.
Functional testing like RGCG or Exacta360 could provide individualized insights, though cost remains a barrier.
MT is still emerging and under-studied — but the science + anecdotes + community data continue to build a compelling case.
Taking ownership of your healing journey, as many in this thread did, is often the first true therapy.

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