Facing Resistance to Standard of Care — Seeking Guidance Beyond Chemo

Fernando Gisone introduced himself after 6 months of chemo and immunotherapy failed to stop the spread of cancer in his abdominal region. While not optimistic about the new treatment plan, he expressed hope in metabolic strategies like keto, fasting, and exercise — all of which he had already begun implementing on his own.

He mentioned being referred by Dr. Thomas Seyfried to the Center for Wellness with Dr. Neil Speight, which uses a press-pulse metabolic therapy approach. Fernando asked the group for guidance on what supplements, dosages, and therapies might help him take control of his cancer journey.

What followed was an outpouring of support, practical suggestions, and layered protocol wisdom from members following the metabolic approach — with references to GKI tracking, supplement stacks, dietary modifications, and off-label drugs.

✅ Key Protocol Components Shared

Vitamin D3 + K2 + Magnesium — Emphasized by multiple members (Bernardo, Lemon P) as foundational and critical for supporting immune function and improving outcomes of immunotherapy.
Ketogenic Diet & GKI Tracking — Fernando was encouraged to measure ketones/glucose and tighten macros (Egg Scrambled, Kimberly, Joseph). Target GKI: <3, ideally <2.
HBOT, Infrared Sauna, Calorie Restriction, and Fasting — Highlighted by Kimberly Smith as part of Seyfried-inspired protocols.
Off-Label & Natural Compounds Mentioned:
Sodium Phenylbutyrate — Kimberly is onboarding this as a glutamine inhibitor.
Castor Oil Packs — Suggested by Odette Rocha for localized therapy (used for thyroid cancer).

✅ Scientific & Philosophical Insights

Vitamin D optimization is seen as non-negotiable due to its immune-modulating effects and synergy with metabolic therapies.
Many members emphasized precision over guessing — measuring ketones, using GKI as a biomarker, and matching interventions to metabolic metrics.
Statin use remains controversial — Kimberly shared her experience of short-term use with benefits and side effects (leg cramps), while Gwen noted liver enzyme changes in her daughter.
Fernando’s ultra-running during chemo was seen as remarkable and inspirational — reinforcing the idea that mindset and activity level can defy clinical expectations.

✅ Practical Wisdom from Community

Test, don’t guess — measure vitamin D levels, track GKI, weigh macros.
Start simple but dial in over time — use a food scale, cut carbs further, get serious about keto structure.
Exercise is a therapy — Fernando’s ultra-marathons mid-chemo underscore how physical movement can be a major pillar of healing.
Be flexible with dosing and cycling — Fenbendazole and melatonin were both discussed with non-daily schedules (e.g., 3 days on, 4 off).
Supplements should be context-driven — especially statins, which have benefits but also risks based on individual tolerance.

✅ Resources & References Shared

Dr. Thomas Seyfried — Referral to Center for Wellness with Dr. Neil Speight (North Carolina, press-pulse model)
Product Links (mentioned indirectly):
Book Reference: How to Starve Cancer by Jane McLelland — used as a guide for off-label medications and supplement targets.

✅ Key Takeaways

Fernando is actively transitioning from a standard protocol to a metabolic therapy-informed approach with support from the group.
Members emphasized precision, personalization, and proactivity — testing GKI, tracking supplements, and individualizing protocols.
The group provided real-world examples of off-label drug use, supplement stacking, and metabolic strategies that have worked for others.
Emotional resilience and physical capability (ultra running) were celebrated as part of Fernando’s healing capacity.
The Center for Wellness and Dr. Neil Speight were validated as a potential clinical ally for metabolic protocols.
Fernando’s post shows how community insight and encouragement can transform fear into empowered action.

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