Pharma Friday: Tren · The AOE Collective

Pharma Friday: Tren

Going to try to make a little informative post about a different compound on Fridays. Thought we’d kick it off with a fun one, and one of my favorites.

Trenbolone aka Tren, Parabolan, 19-nortestosterone (19nor). An absolute powerhouse of a compound in every sense of the word.

Trenbolone is an extremely anabolic compound, greatly increasing the level of IGF-1 in muscle cells combined with an increased sensitivity to IGF-1, it creates the perfect storm for muscle growth.

Tren binds to glucocorticoids (stress hormones) and directly contributes to the inhibition of cortisol (ironic), thus creating an even better environment for muscle growth.

Sounds great, until you realize it’s one of the most toxic compounds you can run. Tren is neurotoxic, hepatoxic, cardiotoxic, and nephrotoxic. In the brain, tren precipitates amyloid plaque formation, a precursor to Dementia and Alzheimer’s.

Side effects include all of the traditional androgenic sides, due to having no estrogenic effect. In men, prostate enlargement, oily skin, and anecdotally male pattern baldness. Due to its ability to bind to progesterone, it can increase breast size and possibly even induce lactation. So have Caber on hand.

It also should be noted the highly psychological effects of tren. Aggression and anxiety being the most reported, anecdotally extremely vivid dreams are reported as well. (I concur with the dreams, they’re pretty fucking wild)

All biomarkers should be monitored on tren, but most importantly liver and kidneys. Excessive abuse of tren can lead to cholestasis, so monitor bilirubin levels.

Tren is a pretty wild ride, you can make crazy gains or get freaky dry and lean while holding loads of muscle. But the trade off is pretty negative, your sleep suffers, your relationships can suffer, your health will definitely suffer.

It’s a deal with the Devil, and it should only be made when you really need it.

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Pharma Friday: Tren