Start at 2mg & be ready to eat! The appetite will come back due to glucagon / amylin; however, about 1 month in, your rat will still have an appetite, but will be FULL after 2-3 bites. Here I dabbled with R to break plateaus; then, went all R. After inflammation showed its ugly face again, I decided to micro-dose both T & R. & although there’s lots of naysayers, it works for my TS! From 237 to 122 & use T on Sun morning & R on Tues pm. Don’t care 🤷‍♀️ what the naysayers say, maintenance is great with a tiny bit of both!