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1 contribution to Outmuscle #foreverstrong
💊 Lilly's New Weight-Loss Pill Just Landed — What is it??
You've probably seen the headlines about Foundayo, Eli Lilly's brand-new weight-loss pill. It got FDA approved back in April, and people are already asking me if it's "the shot, but in pill form." To be candid, I did not know too much about Foundayo until a client asked me about it a few weeks back. Now, with more asking me about it, I decided to do some research. Let's break down what it actually is, how it stacks up against Zepbound and Wegovy, and who it might actually make sense for. 🧬 WHAT IS IT, REALLY? Foundayo (generic name orforglipron) works on the same hormone pathway as Ozempic and Wegovy — it's called GLP-1. That hormone tells your brain "you're full" and slows down digestion, so cravings and portion sizes naturally shrink. The big difference: it's a pill you swallow once a day, not a weekly shot. 💊 WHY THIS ONE'S DIFFERENT - **No needles.** Straight up, it's a tablet. - **No fasting rules.** Take it any time of day, with or without food — unlike the other GLP-1 pill (Rybelsus), which makes you take it on an empty stomach first thing in the morning and wait 30 minutes to eat. - **Simple dosing.** Starts at a tiny 0.8 mg dose and moves up roughly once a month, up to 17.2 mg. 📊 WHAT THE RESEARCH SHOWED - People on the top dose lost about **27 lbs** on average (roughly 12% of body weight) over 72 weeks. - Compare that to Zepbound and Wegovy, which showed **15-22%** body weight loss in their own trials. Foundayo isn't as strong — it only targets GLP-1, while Zepbound also hits a second hormone (GIP) that adds extra punch. - Bonus: waist size, blood pressure, and cholesterol all improved too, not just the scale. ⚠️ SIDE EFFECTS TO KNOW Same GI stuff you'd expect from this drug class — nausea, constipation, diarrhea — most common while the dose is still climbing, and it tends to settle down over time. Same warnings as the shots too (thyroid, pancreas, gallbladder), so it's a conversation for your doctor, not a decision to make solo. 💡 WHERE THIS FITS INTO THE PLAN
1 like • Aug 18
Hey Ron, maybe you can shut some light on this as well. As I understand it, the GLP-1 medication’s mimic a diet similar to one that is high in protein and high in fiber which I think is the focus of at least my current diet protocol with you. As far as I know with this research, the GLP-1 medications slow the digestion of food and increase satiety. If I’m on a high protein, high fiber, diet, the effect is the same, correct? Similarly, getting off the medication’s in a year or two have the effect of increasing hunger and reducing satiety. On top of that resistance training isn’t usually part of the GLP-1 medication regimen, and so instead of preserving muscle and bone mass, if focus on these medication’s are not doing resistance training, they also lose muscle and bone mass. Have you seen that in your research? Essentially, one of the reasons I decided to go with your program is because I need to learn how to do the work of these medications anyway whether I’m on them or off them. If you’re on these medications and get off of them, but have an implemented any kind of diet or resistance training protocol, then eventually you’re back to square one. It also seems like these medication options take a similar amount of time as a high protein, high fiber, diet, so the timeframe is the same for sustained controlled weight loss in both instances. Anyway, let me know what you think. I’d be interested to hear thoughts am I understanding this right?
0 likes • Aug 19
Solid thoughts, thanks Ron! 😁
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Nate Finch
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@nate-finch-3844
Husband, dad, Application Architect @UWMadison , open-source-community-taught dev. Daily: ☝️solvin' problems, ✌️always learnin'👌helpin' people.

Active 7d ago
Joined Jul 6, 2026