Stephen asked for help finding where Dr. Thomas Seyfried directly debunks the idea that cancer feeds on fat. He was re-reading Jane McLelland’s book How to Starve Cancer, where she asserts that cancer can utilize protein and fat (particularly in prostate cancer). The post sparked a nuanced conversation around metabolic theory, cancer bioenergetics, and the contradictions between leading cancer thinkers. The community strongly leaned toward Seyfried’s stance: that cancer cannot ferment fatty acids or ketones due to their mitochondrial dysfunction. Seyfried maintains that glucose and glutamine are the primary fuels. Multiple members reaffirmed that in a state of ketosis—especially under calorie restriction—normal cells thrive on fat/ketones while cancer cells starve. The group also highlighted the need to critically examine Jane McLelland’s broader dietary advice, particularly her promotion of high-fiber plant-based foods, which contradict ketogenic metabolic therapy. Still, some members shared they found her framework useful when paired with Seyfried’s press-pulse approach. ✅ Supplements & Compounds • Ketone Bodies (BHB/AcAc) — Cannot be fermented by cancer cells • Glutamine — Targeted in pulse strategies • Fatty Acids — Not used by cancer for fermentation, per Seyfried • Off-labels mentioned: Ivermectin, DCA, Fenbendazole • Natural Compounds: Sulforaphane, White Button Mushrooms, Curcumin, Resveratrol • Sleep Optimization Aids: Melatonin, grounding sheets, Oura Ring for REM/HRV tracking ✅ Therapies & Strategies • Prolonged Fasting & Keto Adaptation — Several members report improved mitochondrial health and sleep • Press-Pulse Therapy — Combining metabolic pressure with periodic glutamine inhibition • Grounding Sheets & Sleep Tracking — Part of lifestyle stacking • HBOT (Hyperbaric Oxygen Therapy) — Mentioned to improve restorative sleep ✅ Lab Testing & Tumor Profiling • Liquid Biopsies — Some discussion around CTC analysis for targeted protocols • Tumor Tissue Analysis — Mention of Decipher/OncX, but sample quality often limits use

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