To be honest I was unsure of this answer so I went and looked it up. Personally when I had the flu I halted my GLP-1 missing a dose is not going to hurt you. Here is the info I found. So that you can make your own decision. When to Pause: If you have an acute illness accompanied by a high fever, severe body aches, intense fatigue, nausea, or a lack of appetite, the general medical and clinical consensus is to pause non-essential protocols. Your body needs its energy for basic immune defense and recovery rather than processing exogenous (external) compounds. CETAF - Consortium of European Taxonomic Facilities +2 Metabolic and Weight-Loss Peptides (e.g., GLP-1s): If you are taking GLP-1 receptor agonists (such as tirzepatide or semaglutide) and develop a stomach virus, severe nausea, or the flu, doctors and pharmacists often advise temporarily skipping or holding your dose. Combining gastrointestinal illness with GLP-1 medications significantly increases the risk of dehydration and metabolic stress. However, some online communities note that mild colds without stomach symptoms are sometimes managed without skipping, though caution is still required.