@Tony Huge Gotcha. See, the thing that hurts though is despite my disadvantages during this 10 year span on Seroquel, I was living in a sort of "blue zone" in Madison Wisconsin where I was burning an extra thousand calories per day through biking and being involved as a juggler with the circus space. I didn't realize what I had when I decided to move away for a job in Austin Texas. Since coming here my activity levels have plumeted. For the first few years I was here I went to the gym about 5 days a week and continued to juggle off that thousand calorie burn, but it was so difficult to stay on top of that without my community that during the pandemic, when the gym closed, I just totally feel off. Since the pandemic, for more than five years, my life has been totally sedenary, literially laying on a bed in front of a computer and not doing much else. I do have activities two nights a week where I get a good calorie burn, but it's clearly not been enough. Fundamentally the problem is my appetite. I would regularly have 10,000 calorie days. A meal less than 1000 would leave me hungrier than I started. 3000/day was about right. 5000 was common. I just keep telling myself I needed to move more and eat less, so I did workout programs and every dieting strategy possible. But yeah, my biology was working against me in a way I couldn't overcome without being in this sort of perfect situation. Also, I feel like as time goes on it's harder and harder to stay lean. My 100lb gain and sedentary nature could be largely due a slow down from aging. Yeah, I'm working with my doctor to find an alternative to Seroquel. I take my diagnosis very seriously. I want to avoid the worst of what it has to offer. The lamictol is quite good in my opinion. It's basically the only "no brainer" med for this condition. Bascially zero side effects. Great results. Without it I get regular migranes. Instead of Seroquel we recently tried Latuda, but on Reta I couldn't reliability eat the 350 calorie requirement when I take, so next we're going to try Vraylar.