Physical exam look for JVD, edema, etc. obtain chest xray, checking BMP, PBNPT, D Dimer if SOB was acute. Determine the onset of symptoms , what the patient was doing or alwhat they were around. Ask if they have had to change anything such as sleeping upright or with pillows, if they recently traveled . review symptoms with patient, exam lung sounds , medication list, medical history, social and family history. Check for any recent medication changes.