1. What It Is + How It Works Ozone suppositories are made by infusing medical-grade ozone into organic fats or oils (typically ozonated olive or castor oil), which are then formed into small, capsule-like inserts. When used rectally or vaginally, the ozone is absorbed slowly through the colon or vagina into the bloodstream—delivering deep systemic oxygenation, especially to the liver, lymphatic system, and lower pelvic region. This nighttime therapy supports detox, tissue repair, immune recovery, and sleep regeneration without requiring daytime effort or equipment. ​ 2. How to Use It at Home * Store suppositories in the refrigerator to keep firm * Wash hands and use gloves or applicator for hygienic insertion * Insert rectally at bedtime while lying on your side * Remain lying down for at least 1-2 hours * Use 2–4x per week or as directed in your protocol ​ 3. What It Helps Top Health Challenges Ozone Suppositories Support: * Inflammation in liver, colon, or lower spine * Chronic fatigue and immune burnout * Deep tissue detox and post-viral repair * Sleep quality and parasympathetic balance * Glutathione depletion and oxidative stress