💉 Peptide Delivery Systems: Spotlight on Nasal Sprays
When it comes to peptide research, one of the most important variables isn’t just the compound itself — it’s how you deliver it. 📦 Common Delivery Systems - Subcutaneous (SubQ) injection – the most popular method for many peptides, offering steady absorption. - Intramuscular (IM) injection – delivers deeper into muscle tissue, sometimes used for faster or stronger uptake. - Oral capsules – rare for peptides due to breakdown in the digestive tract, though a few analogues are being developed. 👃 Why Researchers Use Nasal Sprays Nasal sprays have become increasingly popular for certain peptides (like Semax and Selank) because: - The nasal mucosa provides a direct pathway for systemic absorption. - They avoid first-pass breakdown in the gut. - They’re convenient, portable, and don’t require needles. - They can be dosed in small, frequent sprays to match short peptide half-lives. ⚠️ Considerations - Peptide stability in solution is lower than in lyophilized form → small batches are best. - Proper reconstitution, sterile handling, and labeling are key to maintain integrity. - Not all peptides are suitable for nasal delivery — this depends on molecular size, stability, and supporting research. 📄 I’ve also prepared a step-by-step SOP for making research nasal sprays from lyophilized powders (Semax / Selank). 👉 See the attachment for details. 🧪 For laboratory research use only. Not for human use