Wernicke’s Encephalopathy
A neurological emergency caused by severe thiamine (vitamin B1) deficiency.
Most commonly seen in:
  • Alcohol use disorder
  • Malnutrition
  • Hyperemesis gravidarum
  • Bariatric surgery patients
  • Dialysis patients
  • Eating disorders
⚠️ The Classic Triad (NREMTP loves this)
Only 10–20% of patients show all three, but you must know them:
1. Confusion
2. Ataxia (unsteady gait)
3. Oculomotor dysfunction
  • Nystagmus
  • Lateral rectus palsy
  • Ophthalmoplegia
🚑 EMS / Clinical Clues
  • AMS
  • Staggering gait or unable to walk
  • Horizontal nystagmus
  • History of alcohol abuse or poor nutrition
  • Hypothermia
  • Hypotension
  • Memory problems
🔥 Critical EMS Treatment
Give thiamine before glucose.
Glucose administration without thiamine can worsen WE by accelerating thiamine consumption.
Dose:
  • 100 mg IV/IM thiamine (commonly available in EMS kits)
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Mike B
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Wernicke’s Encephalopathy
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