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Sep 2 (edited) • General discussion
🧬 ARA-290 (ARA-295) Breakdown
Most people know EPO (erythropoietin) as the hormone that boosts red blood cells, but scientists created a peptide fragment called ARA-290 that keeps the healing benefits without the risks.
💡 What It Does:
- ✅ Calms down inflammation without shutting down your immune system
- ✅ Protects and repairs small nerve fibers (shown in diabetic + autoimmune neuropathy)
- ✅ Supports kidney and vascular health
- ✅ Helps reduce chronic nerve pain and hypersensitivity
⚙️ How It Works: Instead of stimulating red blood cells like EPO, ARA-290 activates the Innate Repair Receptor (IRR) → this kicks off tissue repair + anti-inflammatory pathways.
⚠️ Important:
- Still in the research phase (not FDA approved).
- No big safety concerns so far, since it doesn’t raise hematocrit like EPO.
- Used in studies as a subcutaneous injection.
👉 In short: ARA-290 is about nerve repair, pain reduction, and inflammation control — without the blood-thickening risks of regular EPO.
Research Dosing
- Range: 2 mg – 4 mg per injection
- Frequency: Once daily, or a few times per week, depending on study design
- Route: Subcutaneous injection (similar to many peptide protocols)
- Half-life: ~2 hours, but effects last longer due to receptor activation
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🧬 ARA-290 (ARA-295) Breakdown
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